The rapid growth of e-commerce has fundamentally changed the logistics landscape, creating an increasing demand for faster, more efficient supply chains. One of the most promising strategies to address these challenges is the implementation of cross-docking—a logistics method that minimizes storage time, reduces costs, and accelerates the delivery of goods. This article focuses on the strategic organization of cross-docking in supply chains, specifically between China and the USA, with the goal of speeding up the delivery of goods to warehouses of e-commerce platforms such as Amazon and Walmart. The relevance of the study is underscored by the need for e-commerce platforms to adapt to the ever-evolving customer demands while remaining competitive in the marketplace through logistics optimization.The research highlights key differences between cross-docking and traditional warehousing methods, outlining the advantages of cross-docking for minimizing storage time and cost, especially in international supply chains. Cross-docking eliminates the need for long-term storage by allowing goods to be transferred directly from inbound transportation to outbound shipping, providing companies with faster and more flexible supply chain solutions. These strategies are particularly relevant in the context of the US-China trade, where geographical distance and high consumer demand for timely deliveries present unique logistical challenges.The article details the core principles of cross-docking, identifying its main operational schemes: single-stage and two-stage processes. Each of these methods is explored in terms of their respective benefits for e-commerce platforms, including reduced inventory levels, faster order processing, and cost efficiency. Additionally, the article examines the role of advanced technologies, such as Warehouse Management Systems (WMS), RFID tracking, and automation, in optimizing cross-docking operations. These technologies not only enhance the speed and accuracy of cargo handling but also improve real-time visibility of goods throughout the supply chain.The article also addresses the current challenges faced by companies when implementing cross-docking in e-commerce. These include complex supply chain coordination, inventory visibility, high initial investment costs, and the need for well-trained staff capable of managing rapid cross-docking processes. Despite these obstacles, the article proposes strategic solutions, including improved coordination with customs brokers, trucking companies, and express delivery operators, to ensure smooth operations between China and the USA. The strategic placement of cross-docking facilities near final delivery points, as well as the integration of local logistics operators, is crucial for optimizing last-mile delivery and reducing overall costs.Finally, the article provides real-world examples of successful cross-docking implementation by major companies such as Walmart, Amazon, and DHL, demonstrating the tangible benefits of this logistics method in enhancing supply chain efficiency. The prospects for cross-docking in e-commerce are promising, particularly with the ongoing advancement of automation, IoT, and big data analytics, all of which are expected to further streamline cross-docking processes.In conclusion, cross-docking is positioned as a pivotal logistics strategy for supply chains between China and the USA. The article argues that, while cross-docking is not a one-size-fits-all solution, it offers significant advantages when implemented correctly, providing businesses with faster deliveries, lower costs, and greater supply Chain flexibility